Impact of CYP2C9 and VKORC1 Polymorphisms on Warfarin Sensitivity and Responsiveness in Jordanian Cardiovascular Patients during the Initiation Therapy

Warfarin is an oral anticoagulant frequently used in the treatment of different cardiovascular diseases. Genetic polymorphisms in the CYP2C9 and VKORC1 genes have produced variants with altered catalytic properties. A total of 212 cardiovascular patients were genotyped for 17 Single Nucleotide Polym...

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Publicado en:Genes (Basel)
Autores principales: AL-Eitan, Laith N., Almasri, Ayah Y., Khasawneh, Rame H.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316567/
https://ncbi.nlm.nih.gov/pubmed/30486437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9120578
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