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A Gemini Cationic Lipid with Histidine Residues as a Novel Lipid-Based Gene Nanocarrier: A Biophysical and Biochemical Study
This work reports the synthesis of a novel gemini cationic lipid that incorporates two histidine-type head groups (C(3)(C(16)His)(2)). Mixed with a helper lipid 1,2-dioleoyl-sn-glycero-3-phosphatidyl ethanol amine (DOPE), it was used to transfect three different types of plasmid DNA: one encoding th...
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| Foilsithe in: | Nanomaterials (Basel) |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
MDPI
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6316511/ https://ncbi.nlm.nih.gov/pubmed/30558369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano8121061 |
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