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Finding the Right Way to Target EGFR in Glioblastomas; Lessons from Lung Adenocarcinomas

The EGFR gene is one of the most frequently mutated and/or amplified gene both in lung adenocarcinomas (LUAD) and in glioblastomas (GBMs). Although both tumor types depend on the mutation for growth, clinical benefit of EGFR tyrosine kinase inhibitors (TKIs) has only been observed in LUAD patients a...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Gao, Ya, Vallentgoed, Wies R., French, Pim J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316468/
https://ncbi.nlm.nih.gov/pubmed/30518123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120489
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