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ISG15 Promotes ERK1 ISGylation, CD8+ T Cell Activation and Suppresses Ovarian Cancer Progression

Increased number of tumor-infiltrating CD8+ lymphocytes is associated with improved survival in patients with advanced stage high grade serous ovarian cancer (HGSOC) but the underlying molecular mechanism has not been thoroughly explored. Using transcriptome profiling of microdissected HGSOC tissue...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Yeung, Tsz-Lun, Tsai, Ching Chou, Leung, Cecilia S., Au Yeung, Chi-Lam, Thompson, Melissa S., Lu, Karen H., Freedman, Ralph S., Birrer, Michael J., Wong, Kwong-Kwok, Mok, Samuel C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316352/
https://ncbi.nlm.nih.gov/pubmed/30469497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120464
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