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Mutagenesis Studies and Structure-function Relationships for GalNAc/Gal-Specific Lectin from the Sea Mussel Crenomytilus grayanus

The GalNAc/Gal-specific lectin from the sea mussel Crenomytilus grayanus (CGL) with anticancer activity represents а novel lectin family with β-trefoil fold. Earlier, the crystal structures of CGL complexes with globotriose, galactose and galactosamine, and mutagenesis studies have revealed that the...

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Bibliografski detalji
Izdano u:Mar Drugs
Glavni autori: Kovalchuk, Svetlana N., Buinovskaya, Nina S., Likhatskaya, Galina N., Rasskazov, Valery A., Son, Oksana M., Tekutyeva, Liudmila A., Balabanova, Larissa A.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316223/
https://ncbi.nlm.nih.gov/pubmed/30486373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16120471
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