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Rapid, Reproducible, Quantifiable NMR Metabolomics: Methanol and Methanol: Chloroform Precipitation for Removal of Macromolecules in Serum and Whole Blood

Background: Though blood is an excellent biofluid for metabolomics, proteins and lipids present in blood can interfere with 1d-(1)H NMR spectra and disrupt quantification of metabolites. Here, we present effective macromolecule removal strategies for serum and whole blood (WB) samples. Methods: A va...

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書誌詳細
出版年:Metabolites
主要な著者: McHugh, Cora E., Flott, Thomas L., Schooff, Casey R., Smiley, Zyad, Puskarich, Michael A., Myers, Daniel D., Younger, John G., Jones, Alan E., Stringer, Kathleen A.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316042/
https://ncbi.nlm.nih.gov/pubmed/30558115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo8040093
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