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Genome Editing in Model Strain Myxococcus xanthus DK1622 by a Site-Specific Cre/loxP Recombination System

Myxococcus xanthus DK1622 is a rich source of novel secondary metabolites, and it is often used as an expression host of exogenous biosynthetic gene clusters. However, the frequency of obtaining large genome-deletion variants by using traditional strategies is low, and progenies generated by homolog...

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Bibliographische Detailangaben
Veröffentlicht in:Biomolecules
Hauptverfasser: Yang, Ying-Jie, Singh, Raghvendra Pratap, Lan, Xin, Zhang, Cheng-Sheng, Li, Yue-Zhong, Li, Yi-Qiang, Sheng, Duo-Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316027/
https://ncbi.nlm.nih.gov/pubmed/30404219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom8040137
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