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A Strategy to Replace the Mouse Bioassay for Detecting and Identifying Lipophilic Marine Biotoxins by Combining the Neuro-2a Bioassay and LC-MS/MS Analysis

Marine biotoxins in fish and shellfish can cause several symptoms in consumers, such as diarrhea, amnesia, or even death by paralysis. Monitoring programs are in place for testing shellfish on a regular basis. In some countries testing is performed using the so-called mouse bioassay, an assay that f...

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Publicat a:Mar Drugs
Autors principals: Bodero, Marcia, Gerssen, Arjen, Portier, Liza, Klijnstra, Mirjam D., Hoogenboom, Ron L. A. P., Guzmán, Leonardo, Hendriksen, Peter J. M., Bovee, Toine F. H.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315780/
https://ncbi.nlm.nih.gov/pubmed/30545061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16120501
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