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Anti-CRISPR-Based and CRISPR-Based Genome Editing of Sulfolobus islandicus Rod-Shaped Virus 2

Genetic engineering of viruses has generally been challenging. This is also true for archaeal rod-shaped viruses, which carry linear double-stranded DNA genomes with hairpin ends. In this paper, we describe two different genome editing approaches to mutate the Sulfolobus islandicus rod-shaped virus...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Mayo-Muñoz, David, He, Fei, Jørgensen, Jacob Bruun, Madsen, Poul Kári, Bhoobalan-Chitty, Yuvaraj, Peng, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315595/
https://ncbi.nlm.nih.gov/pubmed/30544778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10120695
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