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CDK 4/6 Inhibitors as Single Agent in Advanced Solid Tumors
Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and ribociclib, interfere with cell cycle progression, induce cell senescence and might promote cancer cell disruption by a cytotoxic T cells-mediated effect. Phase III randomized clinical trials have proven that CDK4/6...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6315195/ https://ncbi.nlm.nih.gov/pubmed/30631751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00608 |
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