CDK 4/6 Inhibitors as Single Agent in Advanced Solid Tumors

Cyclin-dependent kinases (CDK) 4/6 inhibitors, namely abemaciclib, palbociclib, and ribociclib, interfere with cell cycle progression, induce cell senescence and might promote cancer cell disruption by a cytotoxic T cells-mediated effect. Phase III randomized clinical trials have proven that CDK4/6...

Full description

Saved in:
Bibliographic Details
Published in:Front Oncol
Main Authors: Schettini, Francesco, De Santo, Irene, Rea, Carmen G., De Placido, Pietro, Formisano, Luigi, Giuliano, Mario, Arpino, Grazia, De Laurentiis, Michelino, Puglisi, Fabio, De Placido, Sabino, Del Mastro, Lucia
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315195/
https://ncbi.nlm.nih.gov/pubmed/30631751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00608
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items