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Natriuretic Peptide Receptor-C Protects Against Angiotensin II-Mediated Sinoatrial Node Disease in Mice

Sinoatrial node (SAN) disease mechanisms are poorly understood, and therapeutic options are limited. Natriuretic peptide(s) (NP) are cardioprotective hormones whose effects can be mediated partly by the NP receptor C (NPR-C). We investigated the role of NPR-C in angiotensin II (Ang II)-mediated SAN...

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Bibliografiske detaljer
Udgivet i:JACC Basic Transl Sci
Main Authors: Mackasey, Martin, Egom, Emmanuel E., Jansen, Hailey J., Hua, Rui, Moghtadaei, Motahareh, Liu, Yingjie, Kaur, Jaspreet, McRae, Megan D., Bogachev, Oleg, Rafferty, Sara A., Ray, Gibanananda, Kirkby, Adam W., Rose, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314975/
https://ncbi.nlm.nih.gov/pubmed/30623142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.08.004
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