HDAC6 Regulates the MRTF-A/SRF Axis and Vascular Smooth Muscle Cell Plasticity

Cellular plasticity is fundamental in biology and disease. Vascular smooth muscle cell (SMC) dedifferentiation (loss of contractile proteins) initiates and perpetrates vascular pathologies such as restenosis. Contractile gene expression is governed by the master transcription factor, serum response...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Zhang, Mengxue, Urabe, Go, Little, Christopher, Wang, Bowen, Kent, Alycia M., Huang, Yitao, Kent, K. Craig, Guo, Lian-Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
PRECLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314972/
https://ncbi.nlm.nih.gov/pubmed/30623138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.08.010
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