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Role of senescence induction in cancer treatment

Cellular senescence is a form of permanent cell cycle arrest that can be triggered by a variety of cell-intrinsic and extrinsic stimuli, including telomere shortening, DNA damage, oxidative stress, and exposure to chemotherapeutic agents and ionizing radiation. Although the induction of apoptotic ce...

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Bibliographic Details
Published in:World J Clin Oncol
Main Authors: Qin, Shenghui, Schulte, Bradley A, Wang, Gavin Y
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314866/
https://ncbi.nlm.nih.gov/pubmed/30622926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v9.i8.180
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