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Overriding Traditional Electronic Effects in Biocatalytic Baeyer− Villiger Reactions by Directed Evolution
Controlling the regioselectivity of Baeyer− Villiger (BV) reactions remains an ongoing issue in organic chemistry, be it by synthetic catalysts or enzymes of the type Baeyer−Villiger monooxygenases (BVMOs). Herein, we address the challenging problem of switching normal to abnormal BVMO regioselectiv...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314816/ https://ncbi.nlm.nih.gov/pubmed/30044629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b04742 |
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