Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

Collectins such as mannose-binding lectin (MBL) and surfactant protein D (SP-D) become temporarily deposited in extravascular compartments after tissue injury and perform immune-stimulatory or inflammation-limiting functions. However, their turnover mechanisms, necessary to prevent excessive tissue...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Jürgensen, Henrik J., Nørregaard, Kirstine S., Sibree, Megan M., Santoni-Rugiu, Eric, Madsen, Daniel H., Wassilew, Katharina, Krustrup, Dorrit, Garred, Peter, Bugge, Thomas H., Engelholm, Lars H., Behrendt, Niels
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314555/
https://ncbi.nlm.nih.gov/pubmed/30366943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802148
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