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Hepatic VLDL secretion: DGAT1 determines particle size but not particle number, which can be supported entirely by DGAT2

We investigated whether, in view of its activity being expressed on both aspects of the endoplasmic reticulum (ER; dual membrane topology), diacylglycerol acyltransferase 1 (DGAT1) plays a distinctive role in determining the triglyceride (TAG) content of VLDL particles secreted by the liver. Mice in...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Irshad, Zehra, Chmel, Nikola, Adya, Raghu, Zammit, Victor A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314258/
https://ncbi.nlm.nih.gov/pubmed/30397187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M089300
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