Biochemical and structural studies reveal differences and commonalities among cap-snatching endonucleases from segmented negative-strand RNA viruses

Viruses rely on many host cell processes, including the cellular transcription machinery. Segmented negative-strand RNA viruses (sNSV) in particular cannot synthesize the 5′-cap structure for their mRNA but cleave off cellular caps and use the resulting oligonucleotides as primers for their transcri...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Holm, Tobias, Kopicki, Janine-Denise, Busch, Carola, Olschewski, Silke, Rosenthal, Maria, Uetrecht, Charlotte, Günther, Stephan, Reindl, Sophia
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314124/
https://ncbi.nlm.nih.gov/pubmed/30348898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004373
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