AICAR-Induced AMPK Activation Inhibits the Noncanonical NF-κB Pathway to Attenuate Liver Injury and Fibrosis in BDL Rats

BACKGROUND: To evaluate the AMP-activated protein kinase- (AMPK-) mediated signaling and NF-κB-related inflammatory pathways that contribute to cholestatic diseases in the bile duct ligation (BDL) rat model of chronic cholestasis and verify the protective role of 5-Aminoimidazole-4-carboxamide1-β-D-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Can J Gastroenterol Hepatol
Main Authors: Zhu, Haoyang, Chai, Yichao, Dong, Dinghui, Zhang, Nana, Liu, Wenyan, Ma, Tao, Wu, Rongqian, Lv, Yi, Hu, Liangshuo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314002/
https://ncbi.nlm.nih.gov/pubmed/30662889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6181432
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados