Inhibiting Arginine Methylation as a Tool to Investigate Cross-Talk with Methylation and Acetylation Post-Translational Modifications in a Glioblastoma Cell Line

Glioblastomas (GBM) are the most common grade 4 brain tumours; patients have very poor prognosis with an average survival of 15 months after diagnosis. Novel research lines have begun to explore aberrant protein arginine methylation (ArgMe) as a possible therapeutic target in GBM and ArgMe inhibitor...

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Vydáno v:Proteomes
Hlavní autoři: Samuel, Sabrina Francesca, Marsden, Alistair James, Deepak, Srihari, Rivero, Francisco, Greenman, John, Beltran-Alvarez, Pedro
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6313862/
https://ncbi.nlm.nih.gov/pubmed/30347783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/proteomes6040044
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