Comprehensive MicroRNAome Analysis of the Relationship Between Alzheimer Disease and Cancer in PSEN Double-Knockout Mice

PURPOSE: Presenilins are functionally important components of γ-secretase, which cleaves a number of transmembrane proteins. Manipulations of PSEN1 and PSEN2 have been separately studied in Alzheimer disease (AD) and cancer because both involve substrates of γ-secretase. However, numerous clinical s...

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Bibliografiske detaljer
Udgivet i:Int Neurourol J
Main Authors: Ham, Suji, Kim, Tae Kyoo, Ryu, Jeewon, Kim, Yong Sik, Tang, Ya-Ping, Im, Heh-In
Format: Artigo
Sprog:Inglês
Udgivet: Korean Continence Society 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312969/
https://ncbi.nlm.nih.gov/pubmed/30599494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5213/inj.1836274.137
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