The role of p21/CIP1/WAF1 (p21) in the negative regulation of the growth hormone/growth hormone receptor and epidermal growth factor/epidermal growth factor receptor pathways, in growth hormone transduction defect

PURPOSE: Growth hormone transduction defect (GHTD) is characterized by severe short stature, impaired STAT3 (signal transducer and activator of transcription-3) phosphorylation and overexpression of the cytokine inducible SH2 containing protein (CIS) and p21/CIP1/WAF1. To investigate the role of p21...

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Veröffentlicht in:Ann Pediatr Endocrinol Metab
Hauptverfasser: Kostopoulou, Eirini, Rojas Gil, Andrea Paola, Spiliotis, Bessie E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society of Pediatric Endocrinology 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312915/
https://ncbi.nlm.nih.gov/pubmed/30599481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6065/apem.2018.23.4.204
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