Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing

The differentiation of human induced pluripotent stem cells (hiPSCs) to prescribed cell fates enables the engineering of patient-specific tissue types, such as hyaline cartilage, for applications in regenerative medicine, disease modeling, and drug screening. In many cases, however, these differenti...

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Publicat a:Stem Cells
Autors principals: Adkar, Shaunak S., Wu, Chia-Lung, Willard, Vincent P., Dicks, Amanda, Ettyreddy, Adarsh, Steward, Nancy, Bhutani, Nidhi, Gersbach, Charles A., Guilak, Farshid
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312762/
https://ncbi.nlm.nih.gov/pubmed/30378731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2931
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