Endogenous rRNA Sequence Variation Can Regulate Stress Response Gene Expression and Phenotype

Prevailing dogma holds that ribosomes are uniform in composition and function. Here, we show that nutrient limitation-induced stress in E. coli changes the relative expression of rDNA operons to alter the rRNA composition within the actively translating ribosome pool. The most upregulated operon enc...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Kurylo, Chad M., Parks, Matthew M., Juette, Manuel F., Zinshteyn, Boris, Altman, Roger B., Thibado, Jordana K., Vincent, C. Theresa, Blanchard, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312700/
https://ncbi.nlm.nih.gov/pubmed/30282032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.093
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