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Hydroxychloroquine Inhibits Zika Virus NS2B-NS3 Protease

[Image: see text] Zika virus is a mosquito-transmitted flavivirus that causes devastating fetal outcomes in the context of maternal infection during pregnancy. An important target for drugs combatting Zika virus pathogenicity is NS2B-NS3 protease, which plays an essential role in hydrolysis and matu...

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Foilsithe in:ACS Omega
Main Authors: Kumar, Ankur, Liang, Brooke, Aarthy, Murali, Singh, Sanjeev Kumar, Garg, Neha, Mysorekar, Indira U., Giri, Rajanish
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2018
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312647/
https://ncbi.nlm.nih.gov/pubmed/30613818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01002
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