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Dynamic structural rearrangements and functional regulation of voltage‐sensing phosphatase

The voltage‐sensing phosphatase (VSP) consists of a voltage sensor domain (VSD) and a cytoplasmic catalytic region. The latter contains a phosphatase domain and a C2 domain, showing remarkable similarity to the tumour suppressor enzyme PTEN. In VSP, membrane depolarization induces a conformational c...

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Bibliografske podrobnosti
izdano v:J Physiol
Main Authors: Sakata, Souhei, Okamura, Yasushi
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312414/
https://ncbi.nlm.nih.gov/pubmed/30311949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274113
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