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Bayesian inference of protein conformational ensembles from limited structural data

Many proteins consist of folded domains connected by regions with higher flexibility. The details of the resulting conformational ensemble play a central role in controlling interactions between domains and with binding partners. Small-Angle Scattering (SAS) is well-suited to study the conformationa...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Potrzebowski, Wojciech, Trewhella, Jill, Andre, Ingemar
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312354/
https://ncbi.nlm.nih.gov/pubmed/30557358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006641
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