EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal carcinoma

Abnormal metabolism and uncontrolled angiogenesis are two important characteristics of malignant tumors. The occurrence of both events involves many key molecular changes including miRNA. However, EBV encoded miRNAs are rarely mentioned as capable of regulating tumor metabolism and tumor angiogenesi...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Lyu, Xiaoming, Wang, Jianguo, Guo, Xia, Wu, Gongfa, Jiao, Yang, Faleti, Oluwasijibomi Damola, Liu, Pengfei, Liu, Tielian, Long, Yufei, Chong, Tuotuo, Yang, Xu, Huang, Jing, He, Mingliang, Tsang, Chi Man, Tsao, Sai Wah, Wang, Qian, Jiang, Qiang, Li, Xin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312352/
https://ncbi.nlm.nih.gov/pubmed/30557400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007484
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