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Pharmacokinetic/pharmacodynamic (PK/PD) evaluation of tulathromycin against Haemophilus parasuis in an experimental neutropenic guinea pig model

The objective of the study was to develop an ex-vivo PK/PD model of intramuscular (IM) administration of tulathromycin and to test its efficacy against Haemophilus parasuis (H. parasuis) infection in intraperitoneal-inoculated neutropenic guinea pigs. The pharmacokinetics (PKs) of tulathromycin at d...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Zhao, Yongda, Guo, Li-Li, Fang, Binghu, Liu, Baotao
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312216/
https://ncbi.nlm.nih.gov/pubmed/30596709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209177
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