Clinical factors and biomarkers predict outcome in patients with immune-mediated thrombotic thrombocytopenic purpura

Immune-mediated thrombotic thrombocytopenic purpura is characterized by severe thrombocytopenia and microangiopathic hemolytic anemia. It is primarily caused by immunoglobin G type autoantibodies against ADAMTS13, a plasma metalloprotease that cleaves von Willebrand factor. However, reliable markers...

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Vydáno v:Haematologica
Hlavní autoři: Staley, Elizabeth M., Cao, Wenjing, Pham, Huy P., Kim, Chong H., Kocher, Nicole K., Zheng, Lucy, Gangaraju, Radhika, Lorenz, Robin G., Williams, Lance A., Marques, Marisa B., Zheng, X. Long
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312039/
https://ncbi.nlm.nih.gov/pubmed/30171022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.198275
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