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Using Computational Modeling and Experimental Synthetic Perturbations to Probe Biological Circuits

This chapter describes approaches for using computational modeling of synthetic biology perturbations to analyze endogenous biological circuits, with a particular focus on signaling and metabolic pathways. We describe a bottom-up approach in which ordinary differential equations are constructed to m...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Porter, Joshua R., Batchelor, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311997/
https://ncbi.nlm.nih.gov/pubmed/25487101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-1878-2_12
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