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Predicting protein-protein interactions using high-quality non-interacting pairs

BACKGROUND: Identifying protein-protein interactions (PPIs) is of paramount importance for understanding cellular processes. Machine learning-based approaches have been developed to predict PPIs, but the effectiveness of these approaches is unsatisfactory. One major reason is that they randomly choo...

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Библиографические подробности
Опубликовано в: :BMC Bioinformatics
Главные авторы: Zhang, Long, Yu, Guoxian, Guo, Maozu, Wang, Jun
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311908/
https://ncbi.nlm.nih.gov/pubmed/30598096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2525-3
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