Activation of GABA(B) Receptor Suppresses Diabetic Neuropathic Pain through Toll-Like Receptor 4 Signaling Pathway in the Spinal Dorsal Horn

Diabetic neuropathic pain (DNP) is a prevalent complication in diabetes patients. Neuronal inflammation and activation of Toll-like receptor 4 (TLR4) are involved in the occurrence of DNP. However, the underlying mechanisms remain unclear. Downregulation of gamma-aminobutyric acid B (GABA(B)) recept...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Liu, Peng, Yuan, Hong-Bin, Zhao, Shuang, Liu, Fei-Fei, Jiang, Yu-Qing, Guo, Yue-Xian, Wang, Xiu-Li
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311757/
https://ncbi.nlm.nih.gov/pubmed/30647535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6016272
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