SRC-3 Inhibition Blocks Tumor Growth of Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant and lethal disease with few treatment options. Steroid receptor coactivator-3 (SRC-3, also known as NCOA3, AIB1, pCIP, ACTR, RAC3, TRAM1) sits at the nexus of many growth signaling pathways and has been pursued as a therapeutic target for...

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Veröffentlicht in:Cancer Lett
Hauptverfasser: Song, Xianzhou, Chen, Hui, Zhang, Chengwei, Yu, Yang, Chen, Zhongyuan, Liang, Han, Van Buren, George, McElhany, Amy L., Fisher, William E., Lonard, David M., O’Malley, Bert W., Wang, Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311429/
https://ncbi.nlm.nih.gov/pubmed/30423406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.11.012
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