Piezo1 channels are mechanosensors in human fetoplacental endothelial cells

STUDY QUESTION: Does the shear stress sensing ion channel subunit Piezo1 have an important mechanotransduction role in human fetoplacental endothelium? SUMMARY ANSWER: Piezo1 is present and functionally active in human fetoplacental endothelial cells, and disruption of Piezo1 prevents the normal res...

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Detalhes bibliográficos
Publicado no:Mol Hum Reprod
Main Authors: Morley, L C, Shi, J, Gaunt, H J, Hyman, A J, Webster, P J, Williams, C, Forbes, K, Walker, J J, Simpson, N A B, Beech, D J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311101/
https://ncbi.nlm.nih.gov/pubmed/30085186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gay033
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