miR-18a reactivates the Epstein-Barr virus through defective DNA damage response and promotes genomic instability in EBV-associated lymphomas

BACKGROUND: The Epstein-Barr virus (EBV) is closely associated with several types of malignancies. EBV is normally present in the latent state in the peripheral blood B cell compartment. The EBV latent-to-lytic switch is required for virus spread and virus-induced carinogenesis. Immunosuppression or...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Cao, Pengfei, Zhang, Meili, Wang, Lujuan, Sai, Buqing, Tang, Jiuqi, Luo, Zhaohui, Shuai, Cijun, Zhang, Liyang, Li, Zheng, Wang, Yanjin, Li, Guiyuan, Xiang, Juanjuan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311029/
https://ncbi.nlm.nih.gov/pubmed/30594162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5205-9
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