Plasma mitochondrial DNA and metabolomic alterations in severe critical illness

BACKGROUND: Cell-free plasma mitochondrial DNA (mtDNA) levels are associated with endothelial dysfunction and differential outcomes in critical illness. A substantial alteration in metabolic homeostasis is commonly observed in severe critical illness. We hypothesized that metabolic profiles signific...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Johansson, Pär I., Nakahira, Kiichi, Rogers, Angela J., McGeachie, Michael J., Baron, Rebecca M., Fredenburgh, Laura E., Harrington, John, Choi, Augustine M. K., Christopher, Kenneth B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310975/
https://ncbi.nlm.nih.gov/pubmed/30594224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-018-2275-7
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