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Cerebrospinal fluid penetration of very high-dose meropenem: a case report
BACKGROUND: Standard dosing of meropenem (2 g t.i.d.) produces CSF concentrations of only 1–2 mg/L which is inferior to the clinical breakpoint for most Gram-negative bacteria. There is therefore concern that dosing must be increased in order to achieve therapeutic CSF concentrations for bacteria wi...
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| Udgivet i: | Ann Clin Microbiol Antimicrob |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6310956/ https://ncbi.nlm.nih.gov/pubmed/30594199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12941-018-0299-0 |
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