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IRS-1 increases TAZ expression and promotes osteogenic differentiation in rat bone marrow mesenchymal stem cells

Whether insulin receptor substrate 1 (IRS-1) inhibits or promotes the osteogenic proliferation and differentiation in vitro remains controversial. Transcriptional co-activator with PDZ-binding motif (TAZ) plays a vital role in the osteogenesis of bone marrow mesenchymal stem cells (BMSCs), and stron...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Wang, Na, Xue, Peng, Li, Ziyi, Li, Yukun
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310895/
https://ncbi.nlm.nih.gov/pubmed/30530508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.036194
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