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Combined molecular dynamics and neural network method for predicting protein antifreeze activity

Antifreeze proteins (AFPs) are a diverse class of proteins that depress the kinetically observable freezing point of water. AFPs have been of scientific interest for decades, but the lack of an accurate model for predicting AFP activity has hindered the logical design of novel antifreeze systems. To...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kozuch, Daniel J., Stillinger, Frank H., Debenedetti, Pablo G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310784/
https://ncbi.nlm.nih.gov/pubmed/30530650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814945115
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