Interferons Transcriptionally Up-Regulate MLKL Expression in Cancer Cells()

Interferons (IFNs) are key players in the tumor immune response and act by inducing the expression of IFN-stimulated genes (ISGs). Here, we identify the mixed-lineage kinase domain-like pseudokinase (MLKL) as an ISG in various cancer cell lines. Both type I and type II IFNs increase the expression o...

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Bibliographic Details
Published in:Neoplasia
Main Authors: Knuth, Anne-Kathrin, Rösler, Stefanie, Schenk, Barbara, Kowald, Lisa, van Wijk, Sjoerd J.L., Fulda, Simone
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2018
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Original article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310689/
https://ncbi.nlm.nih.gov/pubmed/30521981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.11.002
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