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Lowering line tension with high cholesterol content induces a transition from macroscopic to nanoscopic phase domains in model biomembranes

Chemically simplified lipid mixtures are used here as models of the cell plasma membrane exoplasmic leaflet. In such models, phase separation and morphology transitions controlled by line tension in the liquid-disordered (Ld) + liquid-ordered (Lo) coexistence regime have been described [1]. Here, we...

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Pubblicato in:Biochim Biophys Acta Biomembr
Autori principali: Tsai, Wen-Chyan, Feigenson, Gerald W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310626/
https://ncbi.nlm.nih.gov/pubmed/30529459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2018.11.010
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