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Regulation of major histocompatibility complex gene expression in thyroid epithelial cells by methimazole and phenylmethimazole

Increased expression of major histocompatibility complex (MHC) class-I genes and aberrant expression of MHC class-II genes in thyroid epithelial cells (TECs) are associated with autoimmune thyroid diseases. Previous studies have shown that methimazole (MMI) reduces MHC class-I expression and inhibit...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Giuliani, Cesidio, Bucci, Ines, Montani, Valeria, Singer, Dinah S, Monaco, Fabrizio, Kohn, Leonard D, Napolitano, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310398/
https://ncbi.nlm.nih.gov/pubmed/19837722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-09-0172
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