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Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles

We sought to develop a nanoparticle vehicle that could efficiently deliver small molecule drugs to target lymphocyte populations. The synthesized amphiphilic organic ligand-protected gold nanoparticles (amph-NPs) were capable of sequestering large payloads of small molecule drugs within hydrophobic...

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Detalhes bibliográficos
Publicado no:Biomater Sci
Main Authors: Yang, Yu-Sang Sabrina, Moynihan, Kelly D., Bekdemir, Ahmet, Dichwalkar, Tanmay M., Noh, Michelle M., Watson, Nicki, Melo, Mariane, Ingram, Jessica, Suh, Heikyung, Ploegh, Hidde, Stellacci, Francesco R., Irvine, Darrell J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310171/
https://ncbi.nlm.nih.gov/pubmed/30444251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8bm01208c
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