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SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract
Electrical pacemaker activity generates phasic contractions and motility patterns such as segmentation and peristalsis in the gastrointestinal tract. Pacemaker currents are generated in interstitial cells of Cajal (ICC), which release Ca(2+) from intracellular stores that stimulates Ca(2+)-activated...
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Publicado no: | Sci Signal |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6310020/ https://ncbi.nlm.nih.gov/pubmed/29895614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaq0918 |
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