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SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract

Electrical pacemaker activity generates phasic contractions and motility patterns such as segmentation and peristalsis in the gastrointestinal tract. Pacemaker currents are generated in interstitial cells of Cajal (ICC), which release Ca(2+) from intracellular stores that stimulates Ca(2+)-activated...

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Vydáno v:Sci Signal
Hlavní autoři: Zheng, Haifeng, Drumm, Bernard T., Earley, Scott, Sung, Tae Sik, Koh, Sang Don, Sanders, Kenton M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310020/
https://ncbi.nlm.nih.gov/pubmed/29895614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaq0918
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