ATP-dependent force generation and membrane scission by ESCRT-III and Vps4

The ESCRTs catalyze reverse-topology scission from the inner face of membrane necks in HIV budding, multivesicular endosome biogenesis, cytokinesis, and other pathways. We encapsulated ESCRT-III subunits Snf7, Vps24, and Vps2, and the AAA(+) ATPase Vps4 such that membrane nanotubes reflecting the co...

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Gepubliceerd in:Science
Hoofdauteurs: Schöneberg, Johannes, Pavlin, Mark Remec, Yan, Shannon, Righini, Maurizio, Lee, Il-Hyung, Carlson, Lars-Anders, Bahrami, Amir Houshang, Goldman, Daniel H., Ren, Xuefeng, Hummer, Gerhard, Bustamante, Carlos, Hurley, James H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309985/
https://ncbi.nlm.nih.gov/pubmed/30573630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat1839
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