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(ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition

Protein ADP-ribosylation is a highly dynamic post-translational modification. The rapid turnover is achieved, among others, by ADP-(ribosyl)hydrolases (ARHs), an ancient family of enzymes that reverses this modification. Recently ARHs came into focus due to their role as regulators of cellular stres...

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Détails bibliographiques
Publié dans:Cell Chem Biol
Auteurs principaux: Rack, Johannes Gregor Matthias, Ariza, Antonio, Drown, Bryon S., Henfrey, Callum, Bartlett, Edward, Shirai, Tomohiro, Hergenrother, Paul J., Ahel, Ivan
Format: Artigo
Langue:Inglês
Publié: Cell Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309922/
https://ncbi.nlm.nih.gov/pubmed/30472116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.11.001
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