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Norbornane-based Cationic Antimicrobial Peptidomimetics Targeting the Bacterial Membrane
The design, synthesis and evaluation of a small series of potent amphiphilic norbornane antibacterial agents has been performed (compound 10 MIC = 0.25 μg/mL against MRSA). Molecular modelling indicates rapid aggregation of this class of antibacterial agent prior to membrane association and insertio...
में बचाया:
| में प्रकाशित: | Eur J Med Chem |
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| मुख्य लेखकों: | , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309908/ https://ncbi.nlm.nih.gov/pubmed/30316060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.09.072 |
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