The procoagulant molecule PAI-1 is associated with injury severity and shock in patients with and without traumatic brain injury.

BACKGROUND: Traumatic injury is associated with an increased risk of coagulopathy and venous thrombosis. PAI-1 is a procoagulant molecule that inhibits tPA/uPA, thrombomodulin, and activated protein C. We hypothesized that elevated PAI-1 levels would be associated with increased Injury Severity Scor...

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Bibliographic Details
Published in:J Trauma Acute Care Surg
Main Authors: Condron, Mary, Rowell, Susan, Dewey, Elizabeth, Anderson, Taylor, Lealiiee, Lelani, Farrell, David, Hinson, Holly
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309418/
https://ncbi.nlm.nih.gov/pubmed/30086072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002040
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