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The procoagulant molecule PAI-1 is associated with injury severity and shock in patients with and without traumatic brain injury.
BACKGROUND: Traumatic injury is associated with an increased risk of coagulopathy and venous thrombosis. PAI-1 is a procoagulant molecule that inhibits tPA/uPA, thrombomodulin, and activated protein C. We hypothesized that elevated PAI-1 levels would be associated with increased Injury Severity Scor...
Enregistré dans:
| Publié dans: | J Trauma Acute Care Surg |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309418/ https://ncbi.nlm.nih.gov/pubmed/30086072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002040 |
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