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Normalization of the tumor microenvironment: evidence for tissue inhibitor of metalloproteinase-2 as a cancer therapeutic

Matrix metalloproteinases (MMPs) are members of the Metzincin family of proteases responsible for degrading the extracellular matrix (ECM). In early studies, MMP degradation of the sub-epithelial basement membrane was thought to be tumor cell autonomous and contribute to the invasive behavior of mal...

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Publicat a:Connect Tissue Res
Autors principals: Stetler-Stevenson, William G., Gavil, Noah Veis
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309251/
https://ncbi.nlm.nih.gov/pubmed/24437600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03008207.2013.867339
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