Association between genetic polymorphisms of CYP2C9 and VKORC1 and safety and efficacy of warfarin: Results of a 5 years audit

OBJECTIVE: Genetic polymorphisms of CYP2C9 and VKORC1 play major role in pharmacokinetics and pharmacodynamics of warfarin, respectively. Purpose of our study was to assess the utility of pretesting patients for the above mutations in predicting tendency for bleeding and achieving target INR. METHOD...

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Gepubliceerd in:Indian Heart J
Hoofdauteurs: Biswas, Mansij, Bendkhale, Shital R., Deshpande, Siddharth P., Thaker, Saket J., Kulkarni, Dwarkanath V., Bhatia, Shobna J., Rajadhyaksha, Anjali G., Gogtay, Nithya J., Thatte, Urmila M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018
Onderwerpen:
Clinical and Preventive Cardiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309143/
https://ncbi.nlm.nih.gov/pubmed/30595245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ihj.2018.02.005
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